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Process Develoment Chemist

Employer
Quanta BioDesign, Ltd.
Location
Columbus, Ohio
Salary
$65k-$80k depending on experience
Closing date
Jul 1, 2021

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Field of specialization
Organic
Work Function
Development-Process
Job Type
Full time

Job Details

Job Description

Although specific roles may vary, the overall goal of every scientist at Quanta BioDesign should be the production and/or process development of existing dPEG®s and implementing new dPEG® constructs. The Process Development Chemist position entails being an essential part of our process and scale-up activities, supplying key intermediates, optimizing existing processes and exploring a growing range of new processes for making our unique dPEG® products. Interacting with chemists both in your group, as well as outside of your group and will be a vital link in the development of the dPEG® technology. Excellent planning and problem solving skills are a critical aspect of this position. Chemist must be capable of lifting up to 50lbs on a regular basis.

Qualifications

Theoretical and practical knowledge of general chemistry, organic chemistry, and bio-conjugation principles.

Bachelor’s degree in Chemistry, with 2-5 years of organic chemistry experience required, experience with large scale synthesis preferred.

Effective time management and prioritization skills; able to meet deadlines; able to be flexible with work schedule 

Able to work collaboratively and communicate effectively with others.

Eligibility to work in the United States

Job responsibilities:

  • Contribute to the synthesis or manufacture of key intermediates and final products in accordance with a production schedule.
  • Manage time effectively and be able to prioritize tasks to meet deadlines and product specifications in an environment where work priorities can shift rapidly
  • Set up chemical reactions safely and according to existing knowledge and protocols.
  • Test intermediate products to confirm quality control specifications using HPLC, TLC and NMR where necessary.
  • Prepare laboratory reagents and HPLC buffer solutions.
  • Diligently label in-process and finished products.
  • Maintain Quality Records of all the work that was performed so that the work may be reproduced, and products traced.
  • Ensure the laboratory runs safely and efficiently and maintain a clean environment. This includes cleaning laboratory equipment and glassware.
  • Monitor and report inventories of raw materials, lab supplies, and equipment; report to purchasing in a timely manner.
  • Safely handle toxic, flammable, corrosive, reactive, and cryogenic materials, including laboratory gases.
  • Work in a manner consistent with Good Laboratory Practices and adhering to QBD's Safety, Environmental, and Chemical Hygiene Plans.

 

Company

Quanta BioDesign, Ltd. is a USA-based manufacturing company with a nearly 12,000 ft2 footprint in Plain City, a beautiful northwestern suburb of Columbus, Ohio, the state capital and largest city. Quanta was built upon the passion, creativity, and vision of our founder, Paul D. Davis, Ph.D., who invented and patented the processes of scalably synthesizing discrete, designable dPEG® reagents. With a passion for creative design and a commitment to commercially scale dPEG® products, we currently operate at single batch sizes from research scale to greater than 100kg. Our continuous process improvement philosophy allows us to manufacture dPEG® reagents for 510k clinical diagnostic systems and FDA-approved drugs. We work closely with our clients and their manufacturing partners to develop commercial-scale specifications and analytical methodology, understand and meet production timelines, and participate successfully in qualification audits. As a privately-held company, we have the freedom to pursue our primary mission of stewardship to our customers through the gifts we possess in utilizing organic chemistry and its application to our growing dPEG® technology. Some of the most basic, troublesome problems in drug and diagnostic development include (a) antigenicity, (b) aggregation, (c) non-specific interactions, (d) aqueous solubility, (e) toxicity, and (f) control of distances in modification and conjugation applications. As the creators, designers, and leading innovators of dPEG® technology, we are committed to developing and manufacturing dPEG® architectures that are best suited to solve these and many other problems and ultimately make a difference in the lives of patients with a vast array of medical conditions.

Company info
Website
Telephone
614-792-2958
Location
7470 Montgomery Dr
Plain City
OH
43064
US

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